Melatonin is a hormone naturally produced by the pineal gland in the brain. It plays a crucial role in regulating our sleep-wake cycle, making it a popular supplement for individuals struggling with sleep disorders or jet lag. Understanding how long does melatonin last in the body is important for proper usage. The duration of melatonin's effects can vary depending on several factors, including the dosage, form (such as immediate-release or extended-release), and an individual's metabolism. In general: Onset of Action: Melatonin typically starts working within 30 minutes to an hour after consumption, helping you feel drowsy and ready for sleep. Duration of Effect: The effects of melatonin can last anywhere from 4 to 8 hours. This timeframe provides a window for falling asleep and staying asleep throughout the night. Metabolism and Tolerance: Some individuals may metabolize melatonin faster, leading to a shorter duration of action. Over time, tolerance to melatonin can develop, reducing its effectiveness. It's essential to take melatonin as directed and not exceed the recommended dosage, as doing so can disrupt your natural sleep-wake cycle. Moreover, melatonin is not a long-term solution for sleep issues, and its use should be discussed with a healthcare professional, especially when dealing with chronic sleep problems. Melatonin's effectiveness and duration can vary from person to person, so it's important to pay attention to how your body responds to it. If you have concerns about sleep or melatonin usage, consult a healthcare provider for guidance on the best approach to improve your sleep quality.